An evidence-based approach to positive sentinel node disease: should we ever do a completion node dissection?
نویسندگان
چکیده
منابع مشابه
Sentinel Node Biopsy Alone versus Completion Axillary Node Dissection in Node Positive Breast Cancer: Systematic Review and Meta-Analysis
Introduction. There has been recent interest in validity of completion axillary node dissection after a positive sentinel node. This systematic review aims to ascertain if sentinel lymph node dissection alone was noninferior to axillary lymph node dissection for breast cancer patients who have a positive sentinel node. Method. A systematic review of the electronic databases Embase, MEDLINE, and...
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BACKGROUND Sentinel-lymph-node biopsy is associated with increased melanoma-specific survival (i.e., survival until death from melanoma) among patients with node-positive intermediate-thickness melanomas (1.2 to 3.5 mm). The value of completion lymph-node dissection for patients with sentinel-node metastases is not clear. METHODS In an international trial, we randomly assigned patients with s...
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Background: We investigated the early results of omitting completion axillary lymph node dissection (ALND) for axillary node metastasis-negative (N0), sentinel node (SN) metastasis-positive breast cancer patients. Patients and Methods: 489 patients had invasive N0 breast cancer treated without completion ALND, regardless of their SN metastasis status. Analyses included the associations between ...
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The application and utility of melanoma sentinel lymph node biopsy (SLNB) has evolved significantly since its inception over two decades ago. The current focus has shifted from a staging modality to potentially a therapeutic intervention. Recent research to include large multi-institutional randomized trials have attempted to answer the question: is a completion lymph node dissection (CLND) req...
متن کاملPositive sentinel lymph nodes should be followed by axillary lymph node dissection
The use of sentinel lymph node biopsy (SLNB) has revolutionized breast surgery for early stage breast cancer. SLNB accurately stages the axilla without the morbidity of axillary lymph node dissection (ALND). While allowing those patients with No disease to avoid a potentially morbid dissection, SLNB is a diagnostic procedure which identifies nodal disease and is not designed to replace ALND in ...
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ژورنال
عنوان ژورنال: Melanoma Management
سال: 2019
ISSN: 2045-0885,2045-0893
DOI: 10.2217/mmt-2019-0011